Table 5.
Immunophenotypical characterization of equine mesenchymal stromal cells derived from umbilical cord blood, peripheral blood, and umbilical cord matrix, expressed as the percentage of cells positive for each marker
| Marker | UCB | PB | UCM |
|---|---|---|---|
| CD29pos |
99.6 ± 0.2a |
98.2 ± 0.9a |
98.4 ± 1.0a |
| CD44pos |
99.2 ± 0.2b |
96.6 ± 4.1 |
97.3 ± 1.1 |
| CD73pos |
0.5 ± 0.5c,d |
0.8 ± 0.5 |
0.5 ± 0.1 |
| CD90pos |
99.4 ± 0.3 |
97.8 ± 2.4 |
66.9 ± 27.6a |
| CD105pos |
2.7 ± 3.4 |
1.2 ± 1.6 |
46.2 ± 64.3 |
| MHC-Ipos |
80.3 ± 12.9 |
62.7 ± 24.8c |
77.6 ± 11.8 |
| CD45neg |
0.5 ± 0.3 |
1.8 ± 0.9 |
1.1 ± 1.4 |
| CD79αneg |
0.1 ± 0.1c |
1.0 ± 1.0c |
0.1 ± 0* |
| Monocyte markerneg |
0.2 ± 0.1b,d |
1.3 ± 1.2 |
1.0 ± 1.3 |
| MHC-IIneg | 0.5 ± 0.5 | 0.8 ± 0.7 | 0.8 ± 0.6 |
Indicated source is significantly different from both other sources at least at aP<0.001, bP<0.01, cP<0.05. dOnly significantly different from peripheral blood (PB). Data are presented as average ± standard deviation (n = 6, except for umbilical cord matrix (UCM), n = 2). UCB, umbilical cord blood.