Figure 1.

Cytokine variance within patients as a measure of heterogeneity (n = 63). We calculated the variance of 2 cytokines (interferon-gamma [IFN-γ] and interleukin-2 [IL-2]) within patients, as well as their total variances. The data points indicate the ratios of intrapatient to interpatient variances for the 2 cytokines at baseline (black circles) and during radiotherapy (white circles). The confidence interval is 95%. Based on these confidence intervals, there were no significant differences between the ratios at baseline and the ratios during radiotherapy for either of the cytokines.