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. 2014 Jan 10;5(1):5. doi: 10.1186/scrt394

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Copyright © 2014 Nascimento et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Transplantation of UCX® into MI hearts increased capillary density and decreased apoptosis. Representative images of vehicle–injected (n = 6, A and D) and UCX®-transplanted hearts (n = 5,B and E) stained for CD31 (A and B, red) and for cellular apoptosis (D and E, bright green). (C) CD31-expressing cells were more abundant within the infarcted LV wall of UCX®-transplanted hearts when compared with the vehicle control group. (F) UCX®-transplanted hearts showed fewer apoptotic cells in the apical region when compared with vehicle-injected hearts, suggesting an anti-apoptotic protective effect by the UCX®. Green filter in A and B denotes tissue autofluorescence. *P < 0.05; scale bars = 100 μm.

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