Groups | Serum glucose (mg/dL) | |||
---|---|---|---|---|
0th day | 7th day | 14th day | % variation | |
Normal | 82.32 ± 0.99 | 85.43 ± 1.39 | 83.57 ± 2.22 | −1.51 |
Diabetic control | 360.14 ± 5.06 | 387.58 ± 3.28 | 410.13 ± 2.48 | −13.88 |
Pet Ether extract (500 mg/kg b. w) | 350.55 ± 3.26 | 309.87 ± 2.85 | 266.57 ± 4.10 | 23.95 |
Hydroethanolic extract (500 mg/kg b. w) | 386.47 ± 5.51 | 232.51 ± 3.82** | 177.49 ± 2.00** | 54.07 |
Methanolic extract (500 mg/kg b. w) | 359.54 ± 3.33 | 284.65 ± 2.83** | 201.59 ± 3.38** | 43.93 |
Ethyl Acetate extract (500 mg/kg b. w) | 371.35 ± 2.92 | 325.43 ± 6.43 | 260.53 ± 2.94 | 29.84 |
Glibenclamide (3 mg/kg b. w) | 365.9 ± 3.97 | 248.78 ± 4.16** | 189.92 ± 3.07** | 48.09 |
The values are expressed as mean ± SEM; n = 5 in each group. **P < 0.01 as compared with normal at the same time (one-way ANOVA followed by Dunnett's multiple comparison test).