Table 2.
Effect of extracts of Artemisia amygdalina and glibenclamide on various biochemical parameters in rats.
| Groups | Cholesterol (mg/dL) |
Triglycerides (mg/dL) |
LDL (mg/dL) |
Total protein (g/dL) |
Creatinine (mg/dL) |
|---|---|---|---|---|---|
| Normal | 50.59 ± 2.77 | 62.83 ± 2.46 | 83.35 ± 3.22 | 7.11 ± 0.30 | 0.69 ± 0.05 |
| Diabetic control | 149.33 ± 6.93 | 120.83 ± 4.96 | 189.38 ± 5.61 | 4.20 ± 0.44 | 1.98 ± 0.09 |
| Hydroethanolic extract (250 mg/kg b. w) | 84.32 ± 3.67 | 95.74 ± 5.54 | 132.45 ± 3.35 | 5.75 ± 0.29 | 1.18 ± 0.05 |
| Hydroethanolic extract (500 mg/kg b. w) | 64.83 ± 2.19** | 75.66 ± 4.87** | 101.36 ± 2.95** | 6.12 ± 0.32 | 0.88 ± 0.08** |
| Methanolic extract (250 mg/kg b. w) | 88.12 ± 3.79 | 98.27 ± 5.28 | 142.77 ± 4.23 | 5.15 ± 0.26 | 1.07 ± 0.06 |
| Methanolic extract (500 mg/kg b. w) | 73.35 ± 2.92** | 84.43 ± 6.44** | 128.54 ± 3.46** | 6.67 ± 0.28** | 0.97 ± 0.07** |
| Glibenclamide (3 mg/kg b. w) | 60.83 ± 2.73** | 78.00 ± 2.73** | 92.37 ± 3.67** | 7.03 ± 0.21** | 0.78 ± 0.04** |
The values are expressed as mean ± SEM; n = 5 in each group. **P < 0.01 as compared with diabetic control at the same time (one-way ANOVA followed by Dunnett's multiple comparison test).