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. 2014 May 20;2014:658753. doi: 10.1155/2014/658753

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Copyright © 2014 Huanxing Su et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of lithium treatment and ventral root reimplantation (VRI) on the survival of host motoneurons as revealed by neutral red staining 6 weeks after root avulsion. (A) Normal animals. (B) Animals receiving root avulsion only. (C) Animals receiving ventral root reimplantation (VRI) plus saline injection. (D) Animals receiving ventral root reimplantation (VRI) plus lithium treatment. (E) VRI significantly increased the survival rate of motoneurons compared to controls (*P < 0.001 compared to root avulsion only). Lithium treatment did not further increase the motoneuron survival after VRI. There were no statistically significant differences in the survival rate of motoneurons between saline- and lithium-treated animals. Scale bar: 150 μm.