Table 2.
Drug susceptibility of MAA wild type and MAAΔlprG.
| Drug | M. avium wild type | M. avium ΔlprG |
|---|---|---|
| INHa | Resistant | Resistant |
| RIFa | Resistant | Susceptiblec |
| LXa | Resistant | Resistant |
| KANa | Susceptible | Susceptible |
| PNBa | Resistant | Resistant |
|
| ||
| Determination of MIC (μg/mL) | ||
| PASb | >8.0 (resistant) | >8.0 (resistant) |
| ETHb | >8.0 (resistant) | >8.0 (resistant) |
| CSb | 120.0 (resistant) | 120.0 (resistant) |
| CLAb | 0.5 (susceptible) | 0.5 (susceptible) |
| AZb | 1 (susceptible) | 1 (susceptible) |
| AMKb | 8.0 (resistant) | 4.0 (susceptible)c |
| MOXb | >1.0 (resistant) | 1.0 (resistant) c |
| LZb | 2.0 (resistant) | 0.5 (susceptible) c |
| RBTb | >2.0 (resistant) | 0.25 (susceptible) c |
aDrug resistance was assayed using indirect proportion method on Middlebrook 7H11. bMICs were determined by the resazurin assay. cResitance values lower than those of the M. avium wild type strain.