Figure 2.

Inhibition of N-methyl-D-aspartate (NMDA) or glutamate- (Glu-) induced excitotoxicity by the ethanol extract of Scutellaria baicalensis (S.B.). Lactate dehydrogenase (LDH) activities given off by the damaged neurons into the culture media were measured at 20–24 h after the exposure. Data were calculated as percent of control LDH activity released into the Glu-treated culture medium. Cultures were exposed for 20 min to 350 mM Glu or NMDA in the presence of various concentrations (1, 10, 25, 50, and 100 μg/mL) of the AGR extract and maintained as described in the experimental part.