Figure 7. Regenerative capacity of muscle.

A) Transverse sections of uninjured (Day 0) or injured gastrocnemius muscles 4 days and 6 days post notexin administration. Sections stained with hematoxylin and eosin are shown in the left columns and developmental myosin heavy chain (green), α2-laminin (red) and DAPI (blue) are shown in the right columns. Scale bar  = 50 µm. B) Bars represent the mean +/− S.D. of the total number of regenerating fibers in the uninjured gastrocnemius muscles (Day 0). ***P<0.001 compared with wild-type muscles and ^## P<0.01 compared with mdx^4cv muscles. N = 4 mice for all experiments.