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. 2014 Jun 12;10(6):e1004431. doi: 10.1371/journal.pgen.1004431

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© 2014 Banks et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A) Adjacent sections of gastrocnemius muscles showing the localization of β-dystroglycan and the NODS complex at the sarcolemma of wild-type, desmin^-/-, mdx^4cv and dko skeletal muscles. Scale bar = 50 µm. B) Western analysis of quadriceps muscles reveals an increase in expression of DGC proteins in the desmin^-/- and a reduction in the mdx^4cv and dko muscles. α-DB is α-dystrobrevin and α-sarc. actin is the α-sarcomeric actin loading control. C) Bars show mean +/− S.D. densitometric quantitation of protein expression graphed as a percentage of wild-type. *P<0.05, **P<0.01 compared to wild-type. N = 4–8 for all experiments.