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Effects of acetaminophen (APAP) on (A) O2− and (B) H2O2 levels in Hep3B cells. Measurements were performed following APAP treatment (6 h) using a lucigenin-amplified chemiluminescence method. Control (non-treated), high-dose APAP-treated and 1/10 high-dose APAP-treated cells were examined. Data are presented as mean ± SD from four independent experiments.
