Table 1.

Correlation of intra-articular protein levels with age, serum CRP at second day after surgery, BMI, ASA classification, and period between fracture and punction [h]. Statistical tests refer to correlations to the absolute protein concentrations and the protein concentrations in relation to TPC. Data indicate degradation of extracellular matrix of cartilage and activation of complement over time following fracture. Spearman's ρ and P values are only provided in case of statistical significance; in these cases, all values ranged within the 95% CI.

	Age	Postoperative CRP	BMI	ASA	Period fracture/punction [h]
TPC
Corr. coefficient	—	−0.64	—	—	—
Valid cases	8	8	8	8	8
Signif. (P)	N.s.	0.0428	n.s.	N.s.	N.s.
Aggrecan/ Aggrecan/TPC
Corr. coefficient	—/—	—/—	—/—	—/—	0.74/0.81
Valid cases	8	8	8	8	8
Signif. (P)	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./n.s.	0.001/0.005
bFGF/bFGF/TPC
Corr. coefficient	—/—	—/—	—/—	—/—	—/—
Valid cases	8	8	8	8	8
Signif. (P)	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./n.s.
IL-1β/IL-1β/TPC
Corr. coefficient	—/—	—/0.64	—/—	—/—	—/—
Valid cases	8	8	8	8	8
Signif. (P)	N.s./n.s.	n.s./0.0428	N.s./n.s.	N.s./n.s.	N.s./n.s.
IGF-1/IGF-1/TPC
Corr. coefficient	—/—	—/—	—/—	—/—	—/—
Valid cases	8	8	8	8	8
Signif. (P)	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./n.s.
C3a/C3a/TPC
Corr. coefficient	—/—	—/—	—/—	0.65/—	—/—
Valid cases	8	8	8	8	8
Signif. (P)	N.s./n.s.	N.s./n.s.	N.s./n.s.	0.0391/n.s.	N.s./n.s.
C5a/C5a/TPC
Corr. coefficient	—/—	—/—	—/—	—/—	—/—
Valid cases	8	8	8	8	8
Signif. (P)	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./n.s.
C5b-9/C5b-9/TPC
Corr. coefficient	—/—	—/—	—/—	—/—	—/0.81
Valid cases	8	8	8	8	8
Signif. (P)	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./n.s.	N.s./0.007

BMI: body mass index; ASA: Physical Status Classification System of the American Society of Anesthesiologists; TPC: total protein content; CI: confidence interval; signif. (P): P value for statistical significance; Corr. coefficient: correlation coefficient (Spearman's ρ); N.s.: not significant.