Table 2. Mean absolute expression of human USP26 protein in an array of human normal and neoplastic tissues.
Tissue | Normal | Cancer | Expression ratio | Cancer vs. normal |
Thyroid | 2 | 3193 | 1596.5 | + |
Adrenal | 255 | 2721 | 10.7 | + |
Stomach | 787 | 4618 | 5.9 | + |
Bladder | 4139 | 16057 | 3.9 | + |
Liver | 692 | 2156 | 3.1 | + |
Kidney | 2943 | 7400 | 2.5 | + |
Brain | 4581 | 10681 | 2.3 | + |
Colon | 4604 | 5302 | 1.2 | - |
Cervix | 12383 | 10093 | 1.2 | - |
Uterus | 6415 | 5968 | 1.1 | - |
Skin | 12222 | 7501 | 1.6 | - |
Prostate | 5043 | 1931 | 2.6 | - |
Ovary | 6542 | 1781 | 3.7 | - |
Rectum | 3749 | 1013 | 3.7 | - |
Esophagus | 1233 | 236 | 5.2 | - |
Lung | 4974 | 784 | 6.3 | - |
Breast | 6517 | 519 | 12.6 | - |
Table 2 demonstrates USP26 protein expression in non-testicular tissue including androgen-dependent cancers. Expression ratio is defined as higher expression divided by lower expression. Cancer versus normal column is directional change showing increased or decreased in cancer relative to normal tissue from each organ (+ = increase as compared to normal tissue; − = decrease in expression compared with normal tissue). Expression ratio then used to classify expression pattern (Green = overexpression; White = ratio +2 to −2 (equivocal expression), Red = lower expression compared to normal tissue).