Fig. 1.
The different function of BAFF on effector T cells. Several kinds of peripheral cells may secrete soluble BAFF as shown in the figure. BAFF then promote or inhibit the differentiation of naive CD4+ T cells to Th1, Th2, Th17, T follicular helper T cells and Treg cells, resulting in corresponding consequences. Blue solid arrows represent stimulatory effect, and broken lines represent suppressive effect of BAFF.