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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Hum Genet. 2014 Mar 4;133(7):905–918. doi: 10.1007/s00439-014-1431-7

Table 5.

Detected Best SNP Combinations in HTR3A, HTR3B and SLC6A4 Associated with AD, CD, ND or FTND Based on Cross Validation Consistency (CVC), Prediction Accuracy and Empirical P value from 107 Permutations in AA and EA Sample

Sample SNP Combination Phenotype CVC Prediction Accuracy P value based on 107 permutations
AA HTR3A: rs1020715, rs2276302, rs2085421
HTR3B: rs3758987
SLC6A4: rs25528		 DSM-IV AD 8/10 57.63% 0.00014
HTR3A: rs1985242, rs4938066
SLC6A4: rs25528		 DSM-IV CD 7/10 58.74% 0.0017
HTR3A: rs897685, rs7118530
HTR3B: rs1176744
SLC6A4: rs25528		 DSM-IV ND 7/10 59.66% 0.000057
HTR3A: rs1062613, rs3737457 FTND 10/10 60.34% 0.000017
EA HTR3A: rs4938066
HTR3B: rs3782025
SLC6A4: rs2066713		 DSM-IV AD 9/10 56.05% 0.00074
HTR3A: rs2276302
HTR3B: rs1672717
SLC6A4: rs140701		 DSM-IV CD 7/10 58.27% 0.00029
HTR3A: rs897685
HTR3B: rs1176758
SLC6A4: rs9303628		 DSM-IV ND 8/10 55.18% 0.00075
HTR3A: rs10789980
SLC6A4: rs9303628		 FTND 7/10 55.25% 0.0039