Table 6. Sensitivities and specificities of the different diagnostic tests according to Latent Class Analysis with an estimated 72.4% (95% CI: 65.5, 79.1%) of HAT cases in the study cohort.
Sensitivity % (95% CI) | Specificity % (95% CI) | |
Parasitology† | 82.5 (75.1, 89.6) | 100 (–) |
mAECT whole blood | 66.9 (58.9, 75.2) | 100 (–) |
mAECT buffy coat | 75.9 (67.8, 84.5) | 100 (–) |
PCR filter paper | 73.4 (75.5, 81.6) | 67.0 (50.0, 81.8) |
PCR GE buffer† | 76.9 (69.9, 83.8) | 78.0 (61.8, 91.2) |
Trypanolysis† | 93.5 (87.4, 97.8) | 82.5 (65.3, 96.7) |
CATT≥4 | 96.2 (91.5, 99.4) | 29.1 (14.3, 47.0) |
CATT≥8† | 83.6 (75.0, 91.0) | 79.6 (63.6, 93.4) |
CATT≥16 | 56.0 (44.6, 66.7) | 94.9 (85.2, 100) |
Tests included in main LCA model.