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. 2014 Jun 12;9(6):e99144. doi: 10.1371/journal.pone.0099144

Figure 1. A-NHL biomarker pathway analysis.

Figure 1

The Ingenuity Pathway Analysis (IPA) software package was utilized to identify pathways and specific interactions associated with the serum biomarkers identified in the current and previous reports. Biomarkers evaluated from the current study (rectangles) included CCL19, CXCL11, MCP-2, MIP-1δ, IFN-α, IL-11, IL-29, IP-10, M-CSF, sIL-1R1, C3, HPN, SAA, SAP, MMP-9, TIMP-1 and OC. Biomarkers evaluated based on previous findings (ovals) included IL-6, sCD30, IL-10, sCD23, sCD44, sCD27, CRP, BCA-1/CXCL13 and IgE. Solid lines indicate direct interactions, dashed lines indicate indirect interactions.