Figure 1. Traxoprodil (B, C), arcaine (D, E) and DFMO (F, G) restore memory of Aβ25–35-injected mice, in the novel object recognition task.
(A) Experimental schedule, i.c.v., intracerebroventricular. Traxoprodil and arcaine were administered immediately after training. DFMO was administered 1 hour prior training. Data shown as mean +S.E.M. N = 3 = –5 animals per group for B, D, F. N = 5–9 animals per group for C, E, G. *P<0.05 when compared to control, **P<0.01 and P<0.001when compared to control or Aβ25–35 group.