Figure 2. Spermidine administration reverses the ameliorative effect of arcaine and DFMO on memory of Aβ_25–35-injected mice.

(A) Spermidine was co-administered with arcaine (0.02 nmol/site) immediately after training. (B) (2.7 nmol/site) DFMO was administered 1 hour prior training and immediately after training were injected with spermidine. I.c.v.  =  intracerebroventricular. Data shown as mean + S.E.M. N = 6–7 per group. **p<0.001 when compared vehicle + arcaine or vehicle + DFMO control.