Table 3. Results of meta-analysis in C57BL/6, 129, or 129×C57BL/6 mice.
| Behavioral/Physiological/Biochemical Parameters | C57BL/6 | P value vs. 129 | P value vs. 129×C57BL/6 | 129 | P value vs. 129×C57BL/6 | 129×C57BL/6 | ||||||||||||
| Sample Size | r | 95% Confidence Interval | P value vs. 0 | Sample Size | r | 95% Confidence Interval | P value vs. 0 | Sample Size | r | 95% Confidence Interval | P value vs. 0 | |||||||
| Lower Limit | Upper Limit | Lower Limit | Upper Limit | Lower Limit | Upper Limit | |||||||||||||
| Body Length | 20 | 0.43 | −0.01 | 0.73 | N.S. | - | - | 22 | −0.10 | 0.33 | −0.50 | N.S. | - | - | - | - | - | - |
| Body Temperature | 38 | −0.50 | −0.20 | −0.72 | <0.05 | - | N.S. | - | - | - | - | - | - | 30 | −0.75 | −0.54 | −0.88 | <0.05 |
| Body Weight | 102 | 0.54 | 0.37 | 0.67 | <0.05 | N.S. | - | 38 | −0.49 | −0.17 | −0.71 | <0.05 | - | - | - | - | - | - |
| Body Weight (High Fat Diet) | 23 | 0.69 | 0.36 | 0.87 | <0.05 | - | - | 7 | 0.54 | −0.36 | 0.92 | N.S. | - | - | - | - | - | - |
| Corticosterone Level | 24 | 0.14 | −0.27 | 0.52 | N.S. | - | - | - | - | - | - | - | - | 28 | −0.84 | −0.66 | −0.93 | <0.05 |
| Elevated Plus Maze | 106 | 0.38 | 0.19 | 0.54 | <0.05 | - | N.S. | 44 | 0.08 | −0.24 | 0.38 | N.S. | - | 42 | 0.36 | 0.05 | 0.61 | <0.05 |
| Elevated Plus Maze (Habituated Environment) | 40 | 0.57 | 0.30 | 0.75 | <0.05 | - | - | 44 | −0.08 | 0.24 | −0.38 | N.S. | - | - | - | - | - | - |
| Emergence Test | 40 | −0.58 | −0.31 | −0.76 | <0.05 | - | - | 44 | −0.14 | 0.17 | −0.43 | N.S. | - | - | - | - | - | - |
| Emergence Test (Habituated Environment) | 40 | −0.24 | 0.09 | −0.52 | N.S. | - | - | 44 | −0.10 | 0.21 | −0.40 | N.S. | - | - | - | - | - | - |
| Exploratory Behavior | 40 | 0.19 | −0.15 | 0.48 | N.S. | - | - | 44 | 0.07 | −0.24 | 0.37 | N.S. | - | - | - | - | - | - |
| Fat Mass | 56 | 0.70 | 0.51 | 0.82 | <0.05 | N.S. | - | 23 | 0.61 | 0.18 | 0.84 | <0.05 | - | - | - | - | - | - |
| Fat Mass (High Fat Diet) | 23 | 0.71 | 0.40 | 0.88 | <0.05 | N.S. | - | 7 | 0.79 | 0.10 | 0.97 | <0.05 | - | - | - | - | - | - |
| Food Intake | 31 | −0.17 | 0.21 | −0.51 | N.S. | - | - | 8 | −0.86 | −0.39 | −0.97 | <0.05 | - | - | - | - | - | - |
| Food Intake (High Fat Diet) | 45 | 0.16 | −0.16 | 0.45 | N.S. | - | - | 7 | −0.66 | 0.18 | −0.94 | N.S. | - | - | - | - | - | - |
| Ghrelin Level | 24 | 0.28 | −0.14 | 0.61 | N.S. | - | - | - | - | - | - | - | - | 10 | −0.33 | 0.38 | −0.79 | N.S. |
| Glucose Level | 23 | 0.21 | −0.25 | 0.60 | N.S. | - | - | 8 | 0.22 | −0.58 | 0.80 | N.S. | - | - | - | - | - | - |
| Glucose Level (High Fat Diet) | 37 | 0.13 | −0.24 | 0.46 | N.S. | - | - | 7 | 0.83 | 0.20 | 0.97 | <0.05 | - | - | - | - | - | - |
| Insulin Level | 9 | −0.30 | 0.45 | −0.80 | N.S. | - | - | 8 | −0.20 | 0.59 | −0.79 | N.S. | - | - | - | - | - | - |
| Insulin Level (High Fat Diet) | 23 | 0.53 | 0.11 | 0.79 | <0.05 | - | - | 7 | 0.31 | −0.58 | 0.86 | N.S. | - | - | - | - | - | - |
| Lean Mass | 38 | 0.20 | −0.14 | 0.50 | N.S. | - | - | 8 | 0.36 | −0.46 | 0.85 | N.S. | - | - | - | - | - | - |
| Lean Mass (High Fat Diet) | 9 | 0.55 | −0.18 | 0.89 | N.S. | - | - | 7 | −0.46 | 0.45 | −0.90 | N.S. | - | - | - | - | - | - |
| Leptin Level | 9 | 0.43 | −0.33 | 0.85 | N.S. | - | - | 8 | 0.41 | −0.41 | 0.87 | N.S. | - | - | - | - | - | - |
| Leptin Level (High Fat Diet) | 23 | 0.66 | 0.31 | 0.85 | <0.05 | - | - | 7 | 0.60 | −0.28 | 0.93 | N.S. | - | - | - | - | - | - |
| Leptin Level (per gram fat) | 9 | −0.31 | 0.44 | −0.81 | N.S. | - | - | 8 | 0.00 | −0.70 | 0.70 | N.S. | - | - | - | - | - | - |
| Leptin Level (per gram fat) (High Fat Diet) | 9 | 0.48 | −0.27 | 0.87 | N.S. | - | - | 7 | 0.66 | −0.19 | 0.94 | N.S. | - | - | - | - | - | - |
| Locomotor Activity | 39 | −0.21 | 0.12 | −0.51 | N.S. | - | - | 8 | −0.93 | −0.66 | −0.99 | <0.05 | - | - | - | - | - | - |
| Locomotor Activity (High Fat Diet) | 8 | −0.94 | −0.70 | −0.99 | <0.05 | N.S. | - | 7 | −0.92 | −0.55 | −0.99 | <0.05 | - | - | - | - | - | - |
| Locomotor Activity (Dark Phase) | 16 | −0.72 | −0.29 | −0.91 | <0.05 | N.S. | - | 8 | −0.91 | −0.57 | −0.98 | <0.05 | - | - | - | - | - | - |
| Locomotor Activity (Dark Phase) (High Fat Diet) | 8 | −0.89 | −0.50 | −0.98 | <0.05 | N.S. | - | 7 | −0.85 | −0.27 | −0.98 | <0.05 | - | - | - | - | - | - |
| Motor Coordination | 100 | −0.08 | 0.13 | −0.28 | N.S. | - | - | 110 | −0.15 | 0.05 | −0.33 | N.S. | - | - | - | - | - | - |
| Non-REM Sleep (24 h) | 32 | 0.61 | 0.31 | 0.80 | <0.05 | - | - | 20 | 0.05 | −0.40 | 0.48 | N.S. | - | - | - | - | - | - |
| Non-REM Sleep (Dark Phase) | 16 | 0.49 | −0.01 | 0.79 | N.S. | - | - | 20 | 0.14 | −0.32 | 0.55 | N.S. | - | - | - | - | - | - |
| Non-REM Sleep (Light Phase) | 16 | 0.49 | −0.01 | 0.79 | N.S. | - | - | 20 | −0.08 | 0.38 | −0.50 | N.S. | - | - | - | - | - | - |
| Open Field Test | 160 | 0.24 | 0.09 | 0.39 | <0.05 | - | N.S. | 44 | 0.06 | −0.25 | 0.36 | N.S. | - | 80 | 0.45 | 0.26 | 0.61 | <0.05 |
| Open Field Test (Habituated Environment) | 80 | 0.46 | 0.26 | 0.63 | <0.05 | - | - | 88 | 0.16 | −0.07 | 0.36 | N.S. | - | - | - | - | - | - |
| Oxygen Consumption | 16 | −0.95 | −0.85 | −0.99 | <0.05 | N.S. | - | 8 | −0.98 | −0.88 | −1.00 | <0.05 | - | - | - | - | - | - |
| Oxygen Consumption (High Fat Diet) | 8 | −0.97 | −0.83 | −0.99 | <0.05 | N.S. | - | 7 | −0.99 | −0.95 | −1.00 | <0.05 | - | - | - | - | - | - |
| Response to Handling | 40 | -0.08 | 0.25 | −0.39 | N.S. | - | - | 44 | 0.29 | −0.02 | 0.55 | N.S. | - | - | - | - | - | - |
| Response to Novelty | 40 | 0.26 | −0.07 | 0.54 | N.S. | - | - | 44 | 0.24 | −0.07 | 0.51 | N.S. | - | - | - | - | - | - |
| Response to Supine Restraint | 20 | 0.00 | −0.44 | 0.44 | N.S. | - | - | 22 | 0.00 | −0.42 | 0.42 | N.S. | - | - | - | - | - | - |
| Spatial Learning Function | 20 | −0.16 | 0.31 | −0.56 | N.S. | - | - | 22 | −0.25 | 0.19 | −0.61 | N.S. | - | - | - | - | - | - |
| Startle Response | 20 | 0.15 | −0.31 | 0.56 | N.S. | - | - | 22 | 0.50 | 0.10 | 0.76 | <0.05 | - | - | - | - | - | - |
| Stress Induced Hyperthermia | 22 | 0.46 | 0.05 | 0.74 | <0.05 | - | N.S. | - | - | - | - | - | - | 30 | 0.78 | 0.59 | 0.89 | <0.05 |
| T4 Level | 18 | 0.79 | 0.51 | 0.92 | <0.05 | - | N.S. | - | - | - | - | - | - | 24 | 0.54 | 0.18 | 0.78 | <0.05 |
| Triglyceride Level | 24 | 0.55 | 0.19 | 0.78 | <0.05 | - | - | - | - | - | - | - | - | 24 | −0.17 | 0.25 | −0.54 | N.S. |
| Wakefulness (24 h) | 32 | −0.58 | −0.78 | −0.27 | <0.05 | - | - | 20 | 0.07 | −0.38 | 0.50 | N.S. | - | - | - | - | - | - |
| Wakefulness (Dark Phase) | 16 | −0.17 | 0.36 | −0.61 | N.S. | - | - | 20 | −0.09 | 0.37 | −0.51 | N.S. | - | - | - | - | - | - |
| Wakefulness (Light Phase) | 16 | −0.49 | 0.01 | −0.79 | N.S. | - | - | 20 | 0.22 | −0.25 | 0.60 | N.S. | - | - | - | - | - | - |
r = mean effect size, P value was calculated by Z test.