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. 2014 Jun 12;9(6):e99580. doi: 10.1371/journal.pone.0099580

Table 2. Extensive study for the association of SNPs in the vicinity of TOMM40-APOE region.

SNP ID Position (bp)a Gene Alleleb Genotype countse minor allele frequency OR (95% CI) Allelic P
Cases Controls Cases Controls
rs1871046 50043777 PVRL2 G/A 19/204/374 45/434/796 0.203 0.205 0.983(0.83–1.17) 0.843
rs12978931 50055540 PVRL2 G/A 151/283/158 271/628/376 0.494 0.459 1.152 (1.00–1.32) 0.0445
rs519825 50058619 PVRL2 G/A 14/143/440 18/258/999 0.143 0.115 1.283(1.05–1.57) 0.01577
rs419010 50060160 PVRL2 A/G 261/253/82 489/607/179 0.350 0.378 1.131(0.98–1.31) 0.091
rs4803766 50063008 PVRL2 A/G 72/279/246 159/600/514 0.354 0.361 0.972(0.84–1.12) 0.708
rs11879589 50065116 PVRL2 A/G 0/21/576 0/27/1248 0.018 0.011 1.673(0.94–2.97) 0.07601
rs395908 50065405 PVRL2 T/C 463/121/13 1026/239/10 0.123 0.102 0.805(0.65–1.00) 0.048
rs519113 50068124 PVRL2 C/G 8/109/480 23/246/1006 0.105 0.115 0.904(0.72–1.13) 0.3734
rs6857 50084094 PVRL2 A/G 0/55/542 0/130/1145 0.046 0.051 0.899(0.65–1.24) 0.518
rs10119 50098513 TOMM40 T/C 593/4/0 1267/8/0 0.003 0.003 0.936(0.28–3.12) 0.914
rs449647 50100404 APOE A/T 21/203/368 53/421/786 0.207 0.209 1.013(0.85–1.20) 0.767
rs405509 50100676 APOE C/A 63/277/257 112/545/618 0.338 0.302 1.180(1.02–1.37) 0.027
rs440446 50101007 APOE G/C 23/184/380 49/433/789 0.196 0.209 1.083(0.912–1.289) 0.509
rs769448 50101419 APOE T/C 0/39/554 0/91/1183 0.033 0.036 1.089(0.744–1.595) 0.660
rs769449 50101842 APOE A/G 4/109/484 6/213/1051 0.098 0.089 0.895(0.707–1.131) 0.620
rs7412 50103919 APOE T/C 9/112/470 21/273/970 0.110 0.125 1.152(0.927–1.431) 0.405
rs429358 50103781 APOE C/T 7/90/491 12/230/1033 0.088 0.10 0.877(0.69–1.11) 0.2821
rs4420638 50114786 APOC1 G/A 3/104/489 8/266/1011 0.092 0.107 0.851(0.67–1.07) 0.176
a

Genomic positions are according to NCBI build 36;

b

Minor allele/major allele;

c

The genotype counts are presented as homozygote/heterozygote/wildtype;