Table 4. Infectivity of recombinant HET-s(218-289) F286A and W287 fibrils.
Amount of protein | [Het-s]-infected strains over total tested strains |
no protein | 1/96 |
HET-s(218–289) wt | |
250 µM | 63/96 |
50 µM | 15/72 |
10 µM | 1/48 |
2 µM | 0/24 |
HET-s(218–289) F286A | |
250 µM | 69/96 |
50 µM | 25/72 |
10 µM | 5/48 |
2 µM | 0/24 |
HET-s(218–289) W287A | |
250 µM | 68/96 |
50 µM | 12/72 |
10 µM | 2/48 |
2 µM | 0/24 |