Table 1.
Distribution of the main infectious agents isolated in 268 ascitic fluid samples during the period 2010–2011
| Total (n = 268) (n,%) | Ascitic neutrophil count (median, IQR) | Non-nosocomial episodes (n = 109) (n,%) | Nosocomial episodes (n = 159) (n,%) | p 1 | SBP (n = 57) (n,%) | Bacterascites (n = 140) (n,%) | p 2 | With FQ prophylaxis (n = 27) (n,%) | Without FQ prophylaxis (n = 241) (n,%) | p 3 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Streptococcus (other than S. pneumoniae) |
33 (12.3%) |
70 (21–150) |
17 (15.6%) |
16 (10.1%) |
0.18 |
5 (8.8%) |
18 (12.9%) |
0.42 |
2 (7.4%) |
31 (31.9%) |
0.41 |
|
Streptococcus pneumoniae |
4 (1.5%) |
955 (200–1710) |
4 (3.7%) |
0 (0.0%) |
0.01 |
1 (1.8%) |
1 (0.7%) |
0.51 |
0 (0.0%) |
4 (1.7%) |
0.50 |
|
Enterococcus sp. |
65 (24 .3%) |
75 (25–565) |
15 (13.8%) |
50 (31.4%) |
0.0009 |
13 (22.8%) |
31 (22.1%) |
0.92 |
13 (48.1%) |
52 (21.6%) |
0.02 |
|
Staphylococcus aureus |
7 (2.6%) |
392 (18–815) |
6 (5.5%) |
1 (0.6%) |
0.01 |
0 (0.0%) |
0 (0.0%) |
- |
1 (3.7%) |
6 (2.5%) |
0.71 |
|
Coagulase negative Staphylococcus |
73 (27.2%) |
63 (8–155,5) |
25 (22.9%) |
48 (30.2%) |
0.19 |
13 (22.8%) |
47 (33.6%) |
0.14 |
4 (14.8%) |
69 (28.6%) |
0.13 |
|
Gram positive cocci
|
174 (64.9%) |
77 (10–310) |
67 (61.5%) |
107 (67.3%) |
0.33 |
32 (56.1%) |
91 (65.0%) |
0.24 |
20 (74.7%) |
154 (63.9%) |
0.29 |
|
Escherichia coli |
48 (17.9%) |
129 (86–830) |
20 (18.3%) |
28 (17.6%) |
0.88 |
15 (26.3%) |
21 (15.0%) |
0.06 |
3 (11.1%) |
45 (18.7%) |
0.33 |
|
Klebsiella sp.Enterobacter sp. Serratia sp. |
29 (10.8%) |
92 (58–549) |
10 (9.2%) |
19 (11.9%) |
0.47 |
5 (8.8%) |
10 (7.1%) |
0.70 |
6 (22.2%) |
23 (9.5%) |
0.04 |
|
Pseudomonas sp. |
9 (3.4%) |
59 (44–670) |
0 (0.0%) |
9 (5.7%) |
0.01 |
0 (0.0%) |
5 (3.6%) |
0.15 |
0 (0.0%) |
9 (3.7%) |
0.31 |
|
Gram negative rods
|
91 (34.0%) |
100 (66–660) |
32 (29.4%) |
59 (37.1%) |
0.18 |
23 (40.4%) |
39 (27.9%) |
0.09 |
9 (33.3%) |
82 (34.0%) |
0.94 |
| Anaerobes |
11 (4.1%) |
112 (12–500) |
8 (7.3%) |
3 (1.9%) |
0.03 |
2 (3.5%) |
4 (2.9%) |
0.81 |
0 (0.0%) |
11 (4.6%) |
0.26 |
| Fungi | 7 (2.6%) | 52 (30–55) | 2 (1.8%) | 5 (3.1%) | 0.51 | 0 (0.0%) | 3 (2.1%) | 0.27 | 0 (0.0%) | 7 (2.9%) | 0.37 |
Not all the infectious agents are listed in this table. Since several agents were isolated in the same sample of ascitic fluid, the total may exceed 100%.
1comparison between non-nosocomial and nosocomial episodes.
2comparison between SBP and bacterascites.
3comparison between episodes with and without fluoroquinolone (norfloxacine) prophylaxis.