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. 2012 Oct 18;208(1):130–138. doi: 10.1093/infdis/jis636

Figure 1.

Figure 1.

Cumulative weight gain and Pseudomonas aeruginosa load in mice with cystic fibrosis that received placebo (CF mice), mice without cystic fibrosis that received placebo (non-CF mice), and mice with cystic fibrosis that received PTX3 (CF-PTX3 mice). A, Median daily weight gain over the 12-day period in which vehicle or PTX3 was administered. CF-PTX3 mice gained more weight than CF mice and, like non-CF mice, regained the initial weight lost. Data are pooled from 2 independent experiments (non-CF, n = 17; CF, n = 18; and CF-PTX3, n = 19). B, Total lung colony-forming units (CFU) were counted after 12 days in CF, non-CF, and CF-PTX3 mice. Dots represent CFU per lung in individual mice, and horizontal lines represent median values reported in log scale (non-CF, n = 13; CF, n = 12; CF-PTX3, n = 14). Data are pooled from 2 independent experiments. *P < .05 and **P < .01, by the Mann–Whitney U test.