Figure 2.

Lung inflammatory response after chronic Pseudomonas aeruginosa infection in mice with cystic fibrosis that received placebo (CF mice), mice without cystic fibrosis that received placebo (non-CF mice), and mice with cystic fibrosis that received PTX3 (CF-PTX3 mice). The number (A) and percentage (B) of total leukocytes and of neutrophils, monocytes, and lymphocytes recruited in the airways were determined in bronchoalveolar lavage (BAL) fluid from mice after 12 days of chronic P. aeruginosa lung infection. Dots represent measurements for individual mice, and horizontal lines represent median values. Data are pooled from 2 independent experiments (non-CF, n = 13; CF, n = 12; CF-PTX3, n = 14). P < .05 and **P < .01, by the Mann–Whitney U test.