Table 2.
Clinical study of c-kit+ resident cardiac stem/progenitor cell therapy in heart failure
| Study | Design | Number of patients | Method of delivery | Cell dose | Follow-up period | Results | Reported side effects of therapy |
|---|---|---|---|---|---|---|---|
| Bolli et al. (SCIPIO) [40••] | Open-label, randomized, controlled study | Control (n = 7); cell-treated (n = 16) | Intracoronary | 1 million cells | 4 mo and 12 mo |
↑ LVEF ↓ Infarct size ↓ NYHA class |
No major complications |