Table 3.

Gene expression average fold-change in the whole-blood mRNA relative to total liver lysate (input)

Gene	Expression	Fold-change ± SEM	Range	P value
Cdh5	Endothelial	0.19 ± 0.02	0.17-0.22	<3.5 × 10−2
Tek	Endothelial	0.04 ± 0.01	0.034-0.046	<2.0 × 10−3
Vcam1	Endothelial	0.001 ± 0.004	0.001-0.009	<5.6 × 10−3
Vwf	Endothelial/megakaryocyte	113.40 ± 7.09	106.6-120.7	<3.0 × 10−6
F5	Hepatic/megakaryocyte	1.31 ± 0.06	1.25-1.36	>.3
F8	?	0.01 ± 0.01	0.007-0.012	<1.0 × 10−4

To evaluate the potential contribution of blood contamination to transcript levels of endothelial-specific genes, the tissue lysates of liver samples were set as a reference and the ΔCt values of individual blood samples (n = 4) were related to the mean ΔCt of the reference group. SEM, standard error of the mean.