Table 3.

Multivariate logistic regression analysis to assess factors associated with the realization of de-escalation

Variable	Coefficient	Standard error	Chi-squared	P value	Odds ratio (95% CI)
Sex	−0.32	0.34	0.9	0.33	0.7 (0.4-1.4)
Coma	−0.21	0.47	0.2	0.66	0.8 (0.3-2.0)
Urinary tract infection	0.24	0.61	0.2	0.68	1.3 (0.4-4.2)
Previous antibiotherapy	0.63	0.41	2.3	0.13	1.9 (0.8-4.2)
Appropriate initial antibiotherapy	1.08	0.34	9.9	0.002	2.9 (1.5-5.7)
Narrow-spectrum antibiotic	−4.51	1.04	18.6	<0.001	0.1 (0.0-0.1)
MDR bacterial infection	−1.41	0.52	7.4	0.006	0.2 (0.1-0.7)

CI, confidence interval; MDR, multidrug resistant.