Table 3. Specific types and numbers of mutations found in the different groups.

Groups	Gene	Spec mut.	Type of mut.
TAM	K-RAS	14% (4 of 29)	G>A (3 of 4) G>T (1 of 4)
	P53	34% (10 of 29)	A>G (2 of 10) A>T (1 of 10) C>T (2 of 10) G>A (1 of 10) G>T (1 of 10) Indel (3 of 10)
	PTEN	21% (6 of 29)	C>T (1 of 6) Indel (5 of 6)
EC	K-RAS	5% (2 of 37)	G>A (1 of 2) T>C (1 of 2)
	P53	38% (14 of 37)	A>G (3 of 14) C>T (6 of 14) G>A (1 of 14) T>A (1 of 14) Indel (3 of 14)
	PTEN	59% (22 of 37)	A>C (1 of 22) A>G (1 of 22) A>T (2 of 22) C>A (2 of 22) C>G (2 of 22) C>T (4 of 22) G>T (2 of 22) T>A (1 of 22) T>G (1 of 22) T>C (1 of 22) Indel (5 of 22)

Abbreviations: EC=unexposed to the drug; TAM=tamoxifen.

The number of mutations is based on each individual mutation found in the patients, which includes multiple mutations in the same gene.