Table 1.
Description of study population
|
General |
Frequency |
|
| Number of admissions |
109,216 |
|
| Number of admission-days |
813,739 |
|
| Number of ICUs |
159 |
|
| Number of nosocomial bacteremia during ICU stay |
5,498 (5.03%) |
|
| Number of deaths without NB during ICU stay |
12,678 (11.61%) |
|
| Number of discharges without NB from ICU |
90,142 (82.54%) |
|
| Number of administrative censored admissions |
898 (0.82%) |
|
| Overall risk of nosocomial bacteremia (censored excluded) |
5.08% |
|
| Overall rate of nosocomial bacteremia |
6.75 / 1,000 admission-days |
|
| | ||
|
Risk factors |
Frequency (%) |
Frequency (%) |
| |
(patient level) |
(ICU level) |
|
ICU / hospital level covariates |
|
|
| Number of beds in ICU: |
|
|
| 0 to 10 (reference) |
30,389 (27.82) |
61 (38.36) |
| 11 to 20 |
46,524 (42.60) |
71 (44.65) |
| 21 to 30 |
21,668 (19.84) |
19 (11.95) |
| 31 to 40 |
7,673 (7.03) |
5 (3.14) |
| > 40 |
2,962 (2.71) |
3 (1.89) |
| Number of beds in hospital: |
|
|
| 0 to 500 (reference) |
52,426 (48.00) |
94 (59.12) |
| 501 to 1,000 |
8,259 (7.56) |
10 (6.29) |
| > 1,000 |
48,531 (44.44) |
55 (34.59) |
| Type of hospital: |
|
|
| Private |
6,541 (5.99) |
12 (7.55) |
| Public |
102,675 (94.01) |
147 (92.45) |
| Type of ICU: |
|
|
| Polyvalent (reference) |
96,478 (88.34) |
138 (86.79) |
| Medical |
3,895 (3.57) |
5 (3.14) |
| Surgery |
3,103 (2.84) |
3 (1.89) |
| Coronary |
525 (0.48) |
2 (1.26) |
| Traumatology |
3,273 (3.00) |
6 (3.77) |
| Post-surgery cardiology |
1,834 (1.68) |
4 (2.52) |
| Burn |
108 (0.10) |
1 (0.63) |
| University+teaching hospital (reference) |
67,917 (62.19) |
86 (54.09) |
| Teaching hospital (no university) |
30,089 (27.55) |
52 (32.70) |
| Hospital without teaching/university |
11,210 (10.26) |
21 (13.21) |
|
Calendar year of admission |
|
|
| 2006 (reference) |
14,318 (13.11) |
|
| 2007 |
17,819 (16.32) |
|
| 2008 |
21,559 (19.74) |
|
| 2009 |
25,660 (23.49) |
|
| 2010+ |
29,860 (27.34) |
|
|
Patient level covariates |
|
|
| APACHE II score: |
|
|
| 0 to 10 (reference) |
40,353 (36.95) |
|
| 11 to 20 |
44,654 (40.89) |
|
| 21 to 30 |
19,191 (17.57) |
|
| > 30 |
5,018 (4.59) |
|
| Age (years): |
|
|
| 0 to 40 |
54,477 (49.88) |
|
| 41 to 60 |
12,931 (11.84) |
|
| 61 to 80 (reference) |
29,371 (26.89) |
|
| > 80 |
12,437 (11.39) |
|
| Days in hospital before ICU admission: |
|
|
| 0 to 3 (reference) |
87,208 (79.85) |
|
| 4 to 6 |
5,864 (5.37) |
|
| 7 to 10 |
4,962 (4.54) |
|
| > 10 |
11,182 (10.24) |
|
| Type of diagnosis: |
|
|
| Cardiovascular (reference) |
54,374 (49.79) |
|
| Respiratory |
15,243 (13.96) |
|
| Gastrointestinal |
14,626 (13.39) |
|
| Central nervous system |
17,567 (16.08) |
|
| Other diagnoses |
7,406 (6.78) |
|
| Antibiotic treatment 48 h before and/or after ICU admission |
23,178 (21.22) |
|
| Gender (male) |
71,223 (65.21) |
|
| Origin: community (reference) |
54,996 (50.36) |
|
| Origin: hospital/ICU |
54,220 (49.64) |
|
| Trauma | 8,927 (8.17) | |