Table 2.
Baseline characteristics, nutritional intake, and corticosteroid and inotrope treatment of the study population
| Local protocol (n = 12) | Automated closed-loop (n = 12) | |
|---|---|---|
| Age (years) | 58.3 ± 12.5 | 62.8 ± 16.0 |
| Male sex (n/%) | 9 (75%) | 9 (75%) |
| White ethnicity | 11 (92%) | 12 (100%) |
| Weight (kg) | 83.5 (80.0-89.2) | 81.4 (62.5-97.5) |
| BMI | 27.8 (25.9-30.8) | 27.1 (26.4-31.4) |
| APACHE II score at randomization | 11.2 ± 3.4 | 12.9 ± 5.0 |
| Highest APACHE II score first 24 hours of admission | 13.8 ± 5.0 | 16.2 ± 5.4 |
| Time between admission and study start (days) | 2 (1-7) | 1 (1-3) |
| Previous diabetes | 6 (50%) | 5 (42%) |
| Insulin infusion at study start | 10 (83%) | 10 (83%) |
| Reason for ICU admission | ||
| Medical | 1 (8%) | 3 (25%) |
| After neurosurgery | 4 (33%) | 4 (33%) |
| Trauma | 7 (58%) | 5 (42%) |
| Total energy (kcal/hour) | 66.4 (17.2) | 60.0 (18.4) |
| Total CHO (g/hour) | 7.9 (1.6) | 7.1 (2.2) |
| Feeding interruptions/day | 1 (0-1.5) | 2 (0-2) |
| Corticosteroid treatment | 3 (25%) | 5 (42%) |
| Inotrope treatment | 4 (33%) | 5 (42%) |
Data shown are mean ± SD, median (interquartile range), or number (%). APACHE II, Acute Physiology and Chronic Health Evaluation II; BMI, body mass index.