Table 2.
Control group (N = 299) |
Intervention group (N = 177) |
Differences (P-value) |
|
---|---|---|---|
Predicted delirium chance | 73 ± 22 | 75 ± 19 | 0.50 |
Observed delirium incidence (n,%) | 225 (75%) | 115 (65%) | 0.01 |
Non-delirium: | 74 (25%) | 62 (35%) | 0.38 |
Delirium subtype: | |||
- Hyperactive | 20 (7%) | 6 (3%) | |
- Hypoactive | 81 (27%) | 33 (19%) | |
- Mixed | 124 (41%) | 76 (43%) | |
Number of delirium free days without coma in 28 days | 13 (3 to 27) | 20 (8 to 27) | 0.003 |
Re-intubation (%) | 25 (8%) | 15 (9%) | 0.51 |
Duration mechanical ventilation in hrs. | 118 (39 to 250) | 90 (36 to 229) | 0.24 |
Unplanned removal tubes/lines (%) | 58 (19%) | 21 (12%) | 0.02 |
- Tube | 8 (3%) | 4 (2%) | |
- Gastric tube | 26 (9%) | 14 (8%) | |
- CVC/arterial line | 24 (8%) | 1 (<1%) | |
- Other | 0 (0%) | 2 (1%) | |
Re-admission | 55 (18%) | 20 (11%) | 0.03 |
LOS-ICU | 7 (3 to 13) | 6 (3 to 12) | 0.65 |
LOS-in hospital | 21 (12 to 41) | 20 (11 to 31) | 0.16 |
28-day mortality | 36 (12%) | 13 (7.3%) | 0.03* |
Data are presented as median, interquartile range (IQR), unless mentioned otherwise. * Cox proportional hazard regression analysis adjusted for sepsis and cohort (hazard rate 0.80; 95% CI 0.66 to 0.98.