Table 1A.

Nuclear volume correction.

Mouse lines	WT	S3	S3 + KN62	S3 + KN93	S3 + KN92
Nuclear volume	8607 ± 508	15029 ± 690	10100 ± 729	11000 ± 540	15010 ± 550

Fibroblasts from Wild type (WT) and S3 transgenic mouse have been cultured for 24 h with or without CamKII inhibitors (KN62 and KN93). KN 92 a molecule similar to KN93 but inactive on CamKII, has also been used. Nuclear volume has been evaluated using the Imagej software. Data have been analyzed using the Mann-Whitney test, demonstrating that differences are not statistically different between cells treated with KN92 and wild type but are highly statistically significant between non-treated and cells treated either with KN62 or KN 93. (p-Value < 0.0001). This experiment has been repeated three time.