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. 2014 Jun 13;8:151. doi: 10.3389/fnins.2014.00151

Table 1B.

Nuclear volume correction.

Mouse lines WT G2 G2 + KN62 G2 + KN93 G2 + KN92
Nuclear volume 8607 ± 508 14000 ± 580 9950 ± 695 9900 ± 532 15000 ± 530

Fibroblasts from Wild type (WT) and G2 transgenic mouse have been cultured for 24 h with or without CamKII inhibitors (KN62 and KN93). KN 92 a molecule similar to KN93 but inactive on CamKII, has also been used. Nuclear volume has been evaluated using the Imagej software. Data have been analyzed using the Mann-Whitney test, demonstrating that differences are not statistically different between cells treated with KN92 and wild type but are highly statistically significant between non-treated and cells treated either with KN62 or KN 93. (p-Value < 0.0001). This experiment has been repeated three time.