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. 2013 Dec 5;17(6):R281. doi: 10.1186/cc13142

Table 2.

Data on microcirculation, tissue oxygenation, hemodynamics, blood gas analysis and fluid balance

Parameter Group M 0 M 1 M 2 M 3 M 4 M 5 M 6 M 7 M 8
Tissue oxygenation(tpO 2 mmHg)
 1 (TEA)
 63.8 ± 14.1
 40.2 ± 17.7
 32.5 ± 11.4
 36.3 ± 13.7
 37.1 ± 12.2
 36.8 ± 11.0
 36.2 ± 10.5
 35.2 ± 9.1
 35.0 ± 9.1
2 (Control)
 64.2 ± 14.1
 45.2 ± 21.4
 32.4 ± 16.2
 25.7 ± 15.9*
 22.8 ± 15.6*
 22.2 ± 15.9*
 20.4 ± 15.0*
 20.5 ± 14.3*
 20.4 ± 14.2*
Microcirculation(Flux AU)
 1 (TEA)
 391.9 ± 82.8
 253.3 ± 81.2
 236.1 ± 55.1
 288.9 ± 73.4
 300.4 ± 68.5
 276.2 ± 65.7
 254.1 ± 73.8
 249.9 ± 66.0
 241.5 ± 97.0
2 (Control)
 408.5 ± 88.3
 267.4 ± 103.4
 233.2 ± 56.3
 215.9 ± 104.9*
 201.8 ± 108.1*
 182.4.0 ± 90.0*
 168.6 ± 89.0*
 160.5 ± 80.7*
 150.6 ± 85.7*
HR (min -1 )
 1 (TEA)
 90.5 ± 24.9
 91.9 ± 24.5
 95.4 ± 21.5
 94.4 ± 19.9
 97.7 ± 16.8
 100.7 ± 16.3
 99.4 ± 14.6
 99.3 ± 10.3
 99.4 ± 13.2
2 (Control)
 85.5 ± 13.8
 85.4 ± 14.9
 91.1 ± 16.6
 95.5 ± 16.7
 98.9 ± 15.0
 101.0 ± 13.8
 103.3 ± 14.7
 102.6 ± 16.5
 100.8 ± 11.3
MAP (mmHg)
 1 (TEA)
 72.5 ± 10.6
 74.1 ± 11.5
 76.8 ± 10.6
 74.8 ± 8.7
 74.9 ± 8.4
 70.9 ± 7.2
 67.2 ± 6.6
 64.1 ± 5.3
 62.2 ± 6.2
2 (Control)
 74.7 ± 10.4
 73.3 ± 8.3
 73.5 ± 9.4
 73.4 ± 7.7
 73.1 ± 11.2
 69.6 ± 5.8
 66.5 ± 6.7
 64.2 ± 6.2
 61.9 ± 6.8
CI (L/min)
 1 (TEA)
 4.7 ± 1.3
 4.9 ± 1.3
 5.2 ± 1.1
 5.1 ± 0.9
 5.0 ± 0.9
 5.2 ± 0.9
 4.8 ± 0.7
 4.6 ± 0.5
 4.7 ± 0.8
2 (Control)
 4.6 ± 0.8
 4.6 ± 0.8
 5.1 ± 1.1
 5.1 ± 0.8
 5.1 ± 0.9
 5.1 ± 0.9
 5.2 ± 1.0
 5.2 ± 1.1
 5.2 ± 0.9
SVV (%)
 1 (TEA)
 6.5 ± 2.7
 6.2 ± 1.1
 5.9 ± 1.0
 5.9 ± 1.0
 7.1 ± 1.9
 7.1 ± 1.5
 6.5 ± 1.5
 7.1 ± 1.5
 7.3 ± 1.5
2 (Control)
 6.6 ± 1.6
 6.8 ± 1.6
 6.1 ± 1.3
 6.1 ± 1.3*
 6.9 ± 1.8*
 6.6 ± 0.9*
 6.2 ± 1.6*
 6.8 ± 1.7*
 7.2 ± 2.6*
CVP (mmHg)
 1 (TEA)
 6.7 ± 1.9
 6.6 ± 1.7
 7.0 ± 1.9
 6.6 ± 2.3
 6.5 ± 2.2
 6.4 ± 1.7
 6.6 ± 1.8
 6.7 ± 1.6
 6.6 ± 1.9
2 (Control)
 7.2 ± 2.4
 6.6 ± 1.9
 7.1 ± 2.0
 7.0 ± 1.7
 7.1 ± 2.0
 7.2 ± 2.2
 7.8 ± 2.3
 7.5 ± 2.6*
 8.1 ± 2.9*
p a O 2 (mmHg)
 1 (TEA)
 161.1 ± 67.7
 147.8 ± 24.9
 139.1 ± 14.7
 137.1 ± 12.7
 134.7 ± 16.5
 131.1 ± 17.6
 130.2 ± 18.0
 126.8 ± 17.2
 125.3 ± 17.3
2 (Control)
 159.2 ± 21.2
 145.4 ± 16.8
 141.1 ± 14.9
 138.6 ± 16.7
 128.8 ± 12.7
 124.8 ± 18.2
 122.4 ± 17.1
 118.4 ± 16.6
 115.9 ± 18.7
ScvO 2 (%)
 1 (TEA)
 72.8 ± 8.4
 75.2 ± 8.3
 73.9 ± 10.8
 74.4 ± 11.7
 73.6 ± 13.2
 71.6 ± 12.6
 71.3 ± 9.6
 69.1 ± 9.3
 65.6 ± 12.9
2 (Control)
 81.6 ± 9.9
 77.5 ± 9.6
 79.4 ± 9.8
 77.3 ± 9.4
 70.8 ± 12.3
 73.6 ± 12.2
 73.4 ± 11.0
 74.8 ± 11.5
 72.0 ± 12.5
Lactate(mmol/L)
 1 (TEA)
 0.9 ± 0.3
 0.8 ± 0.2
 0.8 ± 0.2
 0.9 ± 0.2
 0.8 ± 0.2
 0.8 ± 0.2
 0.7 ± 0.2
 0.7 ± 0.2
 0.7 ± 0.2
2 (Control)
 0.9 ± 0.3
 0.9 ± 0.4
 0.9 ± 0.4
 0.9 ± 0.4
 0.8 ± 0.3
 0.7 ± 0.2
 0.6 ± 0.2
 0.6 ± 0.2
 0.6 ± 0.2
Colloids (ml)
 1 (TEA)
 59 ± 141
 121 ± 193
 397 ± 235
 518 ± 203
 676 ± 290
 879 ± 367
 1.088 ± 434
 1.294 ± 460
 1.594 ± 560
2 (Control)
 0 ± 0
 50 ± 132
 174 ± 209
 388 ± 172
 538 ± 156
 768 ± 225
 1.032 ± 171
 1.382 ± 269
 1.694 ± 420
Cristalloids (ml)s
 1 (TEA)
 757 ± 210
 1047 ± 325
 1.268 ± 403
 1.518 ± 460
 1.844 ± 548
 2.347 ± 637
 2.756 ± 748
 3.232 ± 968
 3.606 ± 1.103
2 (Control)
 621 ± 211
 932 ± 292
 1.271 ± 335
 1.415 ± 363
 1.829 ± 357
 2.276 ± 370
 2.788 ± 501
 3.300 ± 663
 0.3800 ± 794
Urine (ml)
 1 (TEA)
 297 ± 271
 406 ± 370
 579 ± 491
 682 ± 552
 1.012 ± 702
 1.294 ± 833
 1.571 ± 1.015
 1.868 ± 1.166
 2.188 ± 1.343
  2 (Control) 206 ± 228 335 ± 337 582 ± 559 762 ± 644 1.065 ± 748 1.424 ± 858 1.876 ± 1.013 2.376 ± 1.136 2.844 ± 1.305

Values for tissue oxygenation (tpo2 (mmHg)), microcirculatory flow (Flux (AU)), Heart rate (HR (min-1)), mean arterial pressure (MAP (mmHg)), cardiac index (CI (L/min)), systemic vascular resistance (SVRi (dynes*sec/cm5/m2)), stroke volume variation (SVV (%)), central venous pressure (CVP (mmHg)), arterial partial oxygen pressure (paO2 (mmHg)), central venous oxygen saturation (ScvO2 (%)), lactate measured in arterial blood gas analysis (mmol/L), cumulative crystalloid infusion (ml), cumulative colloid infusion (ml) and urine output (ml). Data are presented as mean ± standard deviation. *represents statistically significant differenence between treatment groups (P <0.05) at time of measurement. M 0: before induction of the acute pancreatitis, M 1 and 2: after induction of the acute pancreatitis, M 2 to 8: during treatment interval. TEA, thoracic epidural anesthesia.