Table 3.

Histopathologic scoring for severity of acute porcine pancreatitis

Histopathologic severity score of acute pancreatis
Group	Acinar necrosis*	Fatty tissue necrosis*	Inflammation	Edema*	Overall*
Group 1 (TEA)	2 (0–3)	1 (0–2)	2 (0–2)	1 (0–2)	5.5 (3–8)
Group 2 (CONTROL)	3 (0–3)	2 (1–3)	2 (1–3)	1.5 (0.5-3)	8 (5.5-10)
	Acinar necrosis	Fatty tissue necrosis (in relation to plane)	Inflammation (plasma cells, lymphocytes and granulocytes outside parechymal and fatty tissue)	Edema
	0 nil	0 nil	0 nil	0 nil
	1 <10 single necrosis/lobule	1 <1/3 of plane	1 loose infiltrates (≤30 cells/HPF)	1 intralobular edema
	2 ≥10 single necrosis/lobule	2 ≥1/3 to <2/3 of plane	2 moderate infiltrates (30–99 cells/HPF)	2 interacinar edema, ≥2 lobules
* P < 0.05	3 ≥1/3 of plane	3 ≥2/3 of plane	3 dense infiltrates (≥100 cells/HPF)	3 intercellular edema, ≥2 lobules

*P <0.05 representing statistically significant difference. Data are presented as median (range); Pancreatitis Score: 0 (no pancreatitis) to 12 (severe pancreatitis); histopathologic pancreatitis score (0 to 12 points) including acinar necrosis (0 to 3) fatty tissue necrosis (0 to 3), inflammation (0 to 3) and Edema (0 to 3). HPF: High power field; TEA, thoracic epidural anesthesia.