Table 3.

Cox regression analysis for prediction of 28-day mortality

Variable	χ 2	P -value	C index (AUC)	P -value of added value on top of ADM on admission
ADM, admission	18.2	<0.0001	0.69	-
ADM, day 1	21.2	<0.0001	0.70	0.079
ADM, day 2	20.5	<0.0001	0.72	0.113
ADM, day 3	26.4	<0.0001	0.74	0.004
ADM, day 4	29.9	<0.0001	0.75	<0.001

If follow up data were missing, the last observation was carried forward. ADM, Adrenomedullin; AUC, area under the curve.