Table 3.
Treatment indication, modality, and anticoagulation of renal replacement therapy (RRT) in the low-RRT and high-RRT intensive care units (ICUs)
| Low-RRT ICUs (n = 33) | High-RRT ICUs (n = 98) | P value | |
|---|---|---|---|
| Indication of RRT |
|
|
|
| Oliguria |
29 (87.9) |
83 (84.7) |
0.7 |
| High creatinine |
25 (75.8) |
54 (55.1) |
0.04 |
| Acidosis |
24 (72.7) |
72 (73.5) |
0.9 |
| Hyperkalemia |
9 (27.3) |
20 (20.4) |
0.4 |
| Fluid overload |
12 (36.4) |
43 (43.9) |
0.4 |
| Intoxication |
2 (6.1) |
3 (3.0) |
0.4 |
| Modality of RRT |
|
|
|
| Only CRRT during ICU |
20 (60.6) |
52 (53.1) |
0.5 |
| Only IRRT during ICU |
2 (6.1) |
11 (11.2) |
0.4 |
| Both CRRT + IRRT during ICU |
11 (33.3) |
35 (35.7) |
0.8 |
| Time to initiation of RRT from ICU admission (hours) |
17.8 [5.2–33.7] |
13.5 [5.2–33.2] |
0.9 |
| Received anticoagulation |
32 (97) |
83 (84.7) |
0.06 |
| Citrate |
23 (69.7) |
40 (40.8) |
0.004 |
| LMWH |
18 (54.5) |
65 (66.3) |
0.2 |
| Other |
0 |
7 (7.1) |
0.1 |
| None |
4 (12.1) |
27 (27.6) |
0.07 |
| Complications related to RRT | |||
| Complication in insertion of catheter |
8 (24.2) |
10 (10.2) |
0.04 |
| Electrolyte disturbances |
7 (21.2) |
19 (19.4) |
0.8 |
| Hypotension during RRT |
1 (3.0) |
2 (2.0) |
0.7 |
| Bleeding |
2 (6.1) |
1 (1.0) |
0.09 |
| Catheter-related infection | 0 | 1 (1.0) | 0.6 |
Values are expressed as count (%) and median [interquartile range]. CRRT, continuous renal replacement therapy; IRRT, intermittent renal replacement therapy; LMWH, low-molecular-weight heparin.