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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Expert Rev Clin Immunol. 2014 Apr 19;10(6):713–727. doi: 10.1586/1744666X.2014.909730

Table 2.

Exogenous HMGB1-inhibiting agents.

Agents Infection Models Injury
Herbal extract
Danggui LPS/CLP Radiation
Mung bean LPS/CLP Chemical toxemia
Prunella vulgaris CLP -
Herbal components
Nicotine LPS/CLP -
TSN-SS LPS/CLP Cerebral Ischemia
EGCG LPS/CLP Pain
Crush i
I/R
Carbenoxolone CLP I/R
Trauma
Glycyrrhizin LPS Vascular Injury
Chloroquine LPS/CLP I/R
Radiation
Acteoside CLP Chemical toxemia
Chlorogenic acid LPS/CLP Pain
I/R
Emodin-6-O-β-D-glucoside CLP -
Rosmarinic acid (RA) LPS/CLP Radiation
Oxidative
Chemical toxemia
Isorhamnetin-3-O-galactoside LPS/CLP -
Persicarin LPS/CLP I/R
Forsythoside B CLP
Hypoxic
Higenamine -