Table 5.
1 Normal lung |
2 ARDS |
3 COPD |
4 Others |
P (ANOVA) | Post hoc comparison (P ≤0.05) | |
---|---|---|---|---|---|---|
Number of patients | 33 | 13 | 18 | 15 | ||
Number of days | 76 | 54 | 57 | 44 | ||
MV (L/min) | 10.1 (8.0-13.0) | 12.5 (11.0-14.9) | 11.1 (8.3-13.9) | 9.2 (7.2-12.0) | <0.001 | 1 vs. 2; 2 vs. |
VT/PBW (mL/kg) | 8.4 (7.8-9.1) | 8.1 (7.5-9.3) | 9.3 (8.6-11.6) | 7.7 (7.2-9.3) | <0.001 | 1 vs. 3; 2 vs. 3; 3 vs. 4 |
PEEP (cmH2O) | 5 (5-5) | 8 (5-10) | 7 (5-10) | 7 (5-10) | <0.001 | 1 vs. 2; 1 vs. 3; 1 vs. 4 |
FiO2 (%) | 30 (30-30) | 33 (30-38) | 30 (30-33) | 30 (30-34) | <0.001 | 1 vs. 2 |
PINSP (cmH2O) | 21 (16-26) | 24 (16-28) | 22 (17-36) | 24 (21-28) | 0.052 | |
RR (breath/min) | 21 (18-26) | 25 (20-29) | 18 (14-20) | 21 (17-26) | <0.001 | 1 vs. 3; 2 vs. 3; 3 vs. 4 |
RCEXP (s) | 0.66 (0.51-0.78) | 0.52 (0.45-0.61) | 0.86 (0.64-1.12) | 0.53 (0.46-0.65) | <0.001 | 1 vs. 2; 1 vs. 3; 2 vs. 3; 3 vs. 4 |
PaO2/FiO2 (mm Hg) | 322 (278-387) | 213 (173-250) | 273 (206-341) | 253 (222-311) | <0.001 | 1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3; 2 vs. 4 |
PaO2 (mm Hg) | 102 (85-121) | 77 (70-84) | 89 (72-107) | 83 (75-94) | <0.001 | 1 vs. 2; 1 vs. 3; 1 vs. 4; 2 vs. 3 |
pH | 7.38 (7.34-7.44) | 7.40 (7.35-7.43) | 7.33 (7.25-7.37) | 7.37 (7.30-7.42) | <0.001 | 1 vs. 3; 2 vs. 3; 3 vs. 4 |
PaCO2 (mm Hg) | 32 (28-37) | 37 (30-40) | 41 (34-50) | 36 (32-44) | <0.001 | 1 vs. 3; 1 vs. 4 |
Values represent the median of all data. Comparisons used a Kruskal-Wallis analysis of variance (ANOVA) with a Dunn's post hoc test. MV, minute volume, VT/PBW, tidal volume on predicted body weight ratio, PEEP, positive end-expiratory pressure, PINSP, peak inspiratory pressure, RR, respiratory rate, RCEXP, expiratory time constant, vs., versus.