Table 1.
Morphogenetic parameters of finite-element models
| M j | M t | M c | M g | M s | |
|---|---|---|---|---|---|
| Cardiac jelly growth model | 1 | — | 1.0 | — | — |
| Dorsal mesocardial tension model | 1.3 | 0.3 | 1.0 | — | — |
| Myocardial cell-shape change model | 1.3 | — | 1.0 | — | 1.7 |
| Myocardial differential growth model | 1.3 | — | 1.0, 0.9 2 | 1.3 | — |
| Baseline model | 1.3 | 0.8 | 1.0, 0.9 | 1.3 | 1.3 |
1
Initial cardiac jelly growth M j = 1.3 used in all models as the initial condition. Cardiac jelly growth model includes additional growth of 1.5 to generate bending during looping, and the total growth is 1.3 × 1.5 = 2.0.
2
M c = 1.0 for blebbistatin-treated heart and 0.9 for control.