Table 1.
Characteristics of the cohort a
| Characteristics | All patients (N = 1,040) | No selenium (n = 627) | Selenium (n = 413) | P -value |
|---|---|---|---|---|
| Age, (yr), mean ± SD |
67 ± 16 |
67 ± 17 |
67 ± 14 |
0.685 |
| Male, n (%) |
701 (67.4) |
416 (66.3) |
285 (69.0) |
0.371 |
| Severity scores, mean ± SD |
|
|
|
|
| SAPS II, mean ± SD |
48.9 ± 17.3 |
47.7 ± 17 |
50.8 ± 17.7 |
0.001 |
| SOFA, mean ± SD |
8.2 ± 3.5 |
8.2 ± 3.6 |
8.2 ± 3.4 |
0.732 |
| Type of surgery, n (%) |
|
|
|
|
| Gastrointestinal |
424 (40.8) |
204 (32.5) |
220 (53.3) |
<0.001 |
| Cardiothoracic |
326 (31.3) |
228 (36.4) |
98 (23.7) |
<0.001 |
| Trauma |
48 (4.6) |
35 (5.6) |
13 (3.1) |
0.067 |
| Others |
242 (23.3) |
160 (25.5) |
82 (19.9) |
0.3 |
| Comorbidities, n (%) |
|
|
|
|
| Arterial hypertension |
435 (41.8) |
259 (41.3) |
176 (42.6) |
0.676 |
| Diabetes mellitus |
264 (25.4) |
153 (24.4) |
111 (26.9) |
0.37 |
| Cancer |
288 (27.7) |
154 (24.6) |
134 (32.4) |
0.005 |
| Cirrhosis |
71 (6.8) |
39 (6.2) |
32 (7.7) |
0.339 |
| Chronic renal failure |
135 (13) |
79 (12.6) |
56 (13.6) |
0.652 |
| Source of sepsis, n (%) |
|
|
|
|
| Respiratory |
445 (42.8) |
315 (50.2) |
130 (31.5) |
<0.001 |
| Gastrointestinal |
430 (41.3) |
206 (32.9) |
224 (54.2) |
<0.001 |
| Cardiothoracic |
47 (4.5) |
32 (5.1) |
15 (3.6) |
0.264 |
| Wound |
33 (3.2) |
19 (3.0) |
14 (3.4) |
0.746 |
| Urogenital |
23 (2.2) |
12 (1.9) |
11 (2.7) |
0.421 |
| Bloodstream |
11 (1.1) |
6 (1.0) |
5 (1.2) |
0.761 |
| Catheter |
8 (0.8) |
7 (1.1) |
1 (0.2) |
0.156 |
| No focus identified |
2 (0.2) |
1 (0.2) |
1 (0.2) |
1.000 |
| CNS |
4 (0.4) |
2 (0.3) |
2 (0.5) |
0.652 |
| Others | 37 (3.6) | 27 (4.3) | 10 (2.4) | 0.108 |
aCNS: Central nervous system; SAPS II: Simplified Acute Physiology Score II; SD: Standard deviation; SOFA: Sequential Organ Failure Assessment.