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Duration (mean +/− SD) of the loss of righting reflex (A) and time to behavioral recovery (B) following a 20-minute, or 3 or 5-hour IV infusion of AZD-3043 (n = 4, 4 or 3, respectively) or propofol (n = 5, 4 or 5, respectively) in rats (*p<0.05 compared to propofol at the same time-point, Student’s unpaired t-test). The infused dose was adjusted as necessary to maintain a small withdrawal reflex to noxious paw pinch.
