Table 2.
Cardio-respiratory parameters in old and young mechanically ventilated rats
| VT 8 | VT 8 | VT 16 | VT 16 | VT 24 | VT 24 | |
|---|---|---|---|---|---|---|
| beginning | end | beginning | end | Beginning | end | |
| _pH | ||||||
| old | 7.44 (± 0.19) | 7.42 (± 0.02) | 7.39 (± 0.01) | 7.36 (± 0.03) | 7.41 (± 0.18) | 7.24 (± 0.06) |
| young | 7.36 (± 0.02) | 7.34 (± 0.01) | 7.44 (± 0.19) | 7.43 (± 0.13) | 7.40 (± 0.01) | 7.46 (± 0.02) |
| _paCO2 (mmHg) | ||||||
| old | 38.8 (± 2.1) | 35.3 (± 2.6) | 37.8 (± 1.5) | 36.7 (± 1.1) | 36.4 (± 0.9 | 34.8 (± 1.3) |
| young | 47.0 (± 1.9) | 48.7 (± 1.5) | 38.2 (± 1.6) | 38.7 (± 1.0) | 40.1 (± 1.2) | 38.1 (± 1.0) |
| _CVP (mmHg) | ||||||
| Old | 5.1 (± 0.6) | 5.0 (± 0.5) | 5.9 (± 0.6) | 5.3 (± 0.6) | 5.1 (± 0.3) | 6.0 (±0.7) |
| young | 4.9 (± 0.5) | 4.3 (± 0.5) | 5.3 (± 0.6) | 5.1 (± 0.6) | 6.9 (± 0.6) | 5.9 (± 0.5) |
| _Heart rate (bpm) | ||||||
| old | 397 (± 11) | 426 (± 15) | 413 (± 10) | 390 (± 23) | 380 (± 16) | 415 (±10) |
| young | 432 (± 15) | 436 (± 8) | 448 (± 7) | 439 (± 9) | 421 (± 7) | 418 (± 9) |
_Parameters were assessed at the beginning and at the end of the mechanical ventilation period. Tidal volumes (VT) were 8, 16 or 24 ml/kg, respectively.