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Survival in old and young mechanically ventilated rats
| Survival | >3 hours of MV | Complete ventilation period (4 h) | ||
|---|---|---|---|---|
| _Age | young | old | young | old |
| _VT 8 ml/kg | 100% | 100% | 87% | 93% |
| _VT 16 ml/kg | 100% | 87% | 100% | 80% |
| _VT 24 ml/kg | 93% | 73% | 80% | 33% * |
N = 15 per group;
Animals were ventilated with either low (8 ml/kg), high (16 ml/kg) or very high (24 ml/kg) tidal volume (VT). * P = 0.013 vs. old animals with same tidal volume at the same time point.
