Table 3.
Diarrhoea risk factors
|
Exposure |
Number of diarrhoea days on exposure time |
Incidence rate |
Estimated relative risk
a
|
||
|---|---|---|---|---|---|
| (patient-days) | (per 100 patient-days) | 95% CI | P value | ||
| Baseline characteristics | |||||
| SAPS II >48 vs. ≤48 |
702 |
39 |
5.56 |
1.48 (0.64; 3.41) |
0.356 |
| BMI ≥25 kg/m2 vs. <25 kg/m2 |
760 |
39 |
5.13 |
0.77 (0.30; 1.97) |
0.595 |
| Risk factor exposure | |||||
| EN >60% vs. ≤60% energy target |
835 |
59 |
7.07 |
1.75 (1.02; 3.01) |
0.042 |
| Antibiotics: yes vs. no |
817 |
73 |
8.94 |
3.64 (1.26; 10.51) |
0.017 |
| Antifungal drugs: yes vs. no |
142 |
36 |
25.35 |
2.79 (1.16; 6.70) |
0.022 |
| Immunosuppressants: yes vs. no |
69 |
24 |
34.78 |
1.95 (0.57; 6.71) |
0.287 |
| Prokinetics: yes vs. no | 63 | 4 | 6.35 | 1.44 (0.28; 7.38) | 0.659 |
Diarrhoea was defined as at least three liquid or soft stools per day. The exposure to risk factors was present if the factor was observed during the 48 hours preceding a diarrhoea day. BMI, body mass index; CI, confidence interval; EN, enteral nutrition; SAPS, Simplified Acute Physiology Score. aRelative risk estimated with Generalized Estimated Equations logit regression.