Kidney injury biomarkers associated with Crincrease and Crunchanged groups. Urinary and plasma neutrophil gelatinase-associated lipocalin (NGAL) (P < 0.0001) and urinary cystatin C (P = 0.0017) showed an increasing trend, and both Crunchanged and Crincrease were significantly different from Crdecrease (*P < 0.05, **P < 0.01, ***P < 0.001, Tukey's multiple comparison test). Apparent trends in urinary albumin, gamma-glutamyltranspeptidase (GGT), and π-glutahione-S-transferase (π-GST), the other biomarkers, were at a P value of greater than 0.05. Whiskers are at 10th and 90th percentiles. Crincrease, group of patients with a plasma creatinine increase of more than 20% at 24 hours after cardiac arrest; Crunchanged, group of patients in whom plasma creatinine increased no more than 20% or decreased no more than 10% at 24 hours after cardiac arrest.