Table 2.

Simulated virtual-in-patient demographics

Ideal total body water (ITBW), mL	42,000
Initial plasma volume (V10), mL	2,800 (ITBW/15)
Initial expandable space volume (V2e0), mL	8,400 (3 × ITBW/15)
Initial creatinine generation rate (Ġ0), mg/minute	1
Glomerular filtration rates	100, 66.7, 50, 33.3
Insensible water loss rate (İ), mL/day	800
Metabolic water generation rate (Ṁ), mL/day	400
Distribution clearance rate (Cld), mL/minute	200, 10
Initial plasma creatinine concentrations (C10 ≡ C20), mg/dL	1