Table 2.
RRT characteristics, complications, and outcomes by treatment group
| CVVHF (n = 65) | EDHF (n = 80) | P -value | |
|---|---|---|---|
| Blood flow, ml/minute |
213.03 ± 21.72 |
231.43 ± 18.26 |
0.005 |
| Ultrafiltration per hour, ml |
149.09 ± 66.58 |
241.84 ± 92.64 |
<0.001 |
| Ultrafiltration per day, L |
3.20 ± 1.59 |
2.84 ± 1.09 |
0.110 |
| Replacement flow, ml/kg/h |
29.42 ± 6.10 |
40.14 ± 8.19 |
<0.001 |
| Replacement flow, L/h |
19.32 ± 5.32 |
26.32 ± 6.64 |
<0.001 |
| Replacement flow, L/day |
4.64 ± 1.28 |
2.65 ± 0.75 |
<0.001 |
| The total time of renal support, days |
3.86 ± 1.55 |
3.41 ± 1.58 |
0.112 |
| Anticoagulant, n (%) |
|
|
|
| None |
10 (15.38) |
20 (25.00) |
0.355 |
| Heparin/low molecular heparin |
35 (53.85) |
37 (46.25) |
|
| Others |
20 (27.69) |
23 (28.75) |
|
| Fluid balance during first 72 hours RRT, L |
-0.46 ± 0.67 |
0.15 ± 0.37 |
0.019 |
| MAP during first 72 hours RRT, mm Hg |
89.73 ± 20.01 |
83.79 ± 19.26 |
0.137 |
| Complications, n (%) |
|
|
|
| Bleeding |
14 (21.54) |
10 (12.50) |
0.145 |
| Hypotension |
10 (15.39) |
21 (26.25) |
0.112 |
| Hypokalemia |
33 (50.77) |
31 (38.75) |
0.147 |
| Hypophosphatemia |
36 (55.38) |
23 (28.75) |
0.001 |
| Primary outcome, n (%) |
|
|
|
| Renal recovery-60 days |
33 (50.77) |
26 (32.50) |
0.026 |
| Mortality-60 days | 29 (44.62) | 37 (46.25) | 0.844 |
RRT, renal replacement therapy; MAP, mean arterial pressure; CVVHDF, continuous venovenous hemodiafiltration; CVVHF, continuous venovenous hemofiltration.