Table 4.
Disease severity, organ dysfunction and mortality for JAAM DIC score on inclusion day (day 1)
| JAAM DIC score | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| 0 (n = 19) | 1 (n = 89) | 2 (n = 143) | 3 (n = 81) | 4 (n = 59) | 5 (n = 105) | 6 (n = 59) | 7 (n = 19) | 8 (n = 50) | |
| APACHE II score | 22.3 ± 7.8 | 20.2 ± 7.6 | 21.8 ± 7.5 | 23.7 ± 8.6 | 23.4 ± 7.9 | 26.1 ± 9.1bc | 25.1 ± 7.0b | 25.0 ± 9.1 | 26.0 ± 9.2b |
| SIRS score | 1.7 ± 0.5 | 2.8 ± 1.0 | 3.2 ± 0.7 | 3.4 ± 0.7 | 2.9 ± 1.0ad | 3.3 ± 0.7ab | 3.5 ± 0.5ab | 2.7 ± 1.0a | 3.6 ± 0.5abc |
| SOFA score | 6.5 ± 3.7 | 5.7 ± 3.3 | 6.7 ± 2.9 | 8.0 ± 3.5 | 9.4 ± 3.4bc | 10.0 ± 4.2abcd | 11.4 ± 3.2abcd | 11.5 ± 3.4abcd | 11.9 ± 3.6abcd |
| SOFA peak score during study period | 6.8 ± 3.8 | 6.1 ± 3.4 | 7.4 ± 3.3 | 8.7 ± 3.6 | 10.0 ± 3.5bc | 11.0 ± 4.2abcd | 11.9 ± 3.3abcd | 12.3 ± 3.1abcd | 13.0 ± 3.8abcd |
| MODS (%) | 42.1 | 32.6 | 37.1 | 54.3 | 55.9bc | 61.9bc | 72.9abcd | 63.2b | 76.0abcd |
| 28-day mortality (%) | 5.3 | 10.1 | 18.9 | 19.8 | 27.1b | 37.1abcd | 27.1ab | 31.6ab | 28.0ab |
| Hospital mortality (%) | 10.5 | 14.6 | 25.2 | 25.9 | 30.5ab | 43.8abcd | 35.6ab | 42.1ab | 38.0ab |
APACHE, Acute Physiology and Chronic Health Evaluation; DIC, disseminated intravascular coagulation; JAAM, Japanese Association for Acute Medicine; MODS, multiple organ dysfunction syndrome; SIRS, Systemic Inflammatory Response Syndrome; SOFA, Sequential Organ Failure Assessment. Analyses of variance of APACHE II, SIRS and SOFA are as follows: P <0.001, aP <0.05 versus 0, bP <0.05 versus 1, cP <0.05 versus 2, dP <0.05 versus 3.